Stimulants - Stimulants increase respiration rate which permits an increased dose of opiates than would usually be utilised. When the stimulant wears off first then the opiate may triumph over the consumer and lead to respiratory arrest.Flipping the path with the R2 and R1 bonds brings about the R- and S- enantiomers of O-Desmethyltramadol. O-DMST … Read More